Dear colleagues,
The following news items have been published in the previous month:
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17 Jul 2024:
What agents to test and which to avoid!
Occasionally colleagues request information from EUCAST on what agents to test and which to avoid.
EUCAST has hitherto refrained from giving firm advice simply because
national traditions, availability and cost of agents, and guidelines
vary to the extent where a general prescriptive advice becomes
inappropriate. "Read between the lines:" agents which EUCAST
consider unsuitable for therapy of a species or a group of species will
typically lack numerical breakpoints in EUCAST tables. Agents
considered appropriate for some or several types of infection with the
species (or group of species) will have numerical breakpoints. An "IE"
is a subtle encouragement together with a reminder that EUCAST could not
find evidence
for the appropriateness of the agent, whereas a "dash" is firm
recommendation from EUCAST to avoid the agent.
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17 Jul 2024:
CMI Podcast on EUCAST achievements
Communicable E5 - Beauty is in the 'I' of the beholder: EUCAST updates with Sören Gatermann and Christian Giske, discussing pros and cons with Angela Huttner and Mark Bonten.
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15 Jul 2024:
Twenty years with EUCAST AFST
Twenty Years in EUCAST Anti‑Fungal Susceptibility Testing: Progress
& Remaining Challenges. Maiken Cavling Arendrup, Jesus Guinea,
Joseph Meletiadis. Mycopathologia (2024) 189:64. Follow this link for
free access: https://rdcu.be/dNwq5.
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14 Jul 2024:
S, I and R and surveillance of AMR
This is to clarify how "susceptibility (S and I)" and "resistance (R)" should be reported in AMR surveillance with the EUCAST definitions of S I and R.
With the EUCAST definitions, the tradition to report
"non-susceptibility" as the joint rate of %I and %R is abandoned.
Previously (pre-2019) it was tempting to lump I and R together whereas
with the modern EUCAST definitions, both S and I are susceptible
categories and breakpoints have been systematically reviewed and revised
to reflect this. In antimicrobial resistance surveillance there are
three alternatives:
- Report only %R
- Report %S, %I and %R separately
- If for some reason lumping categories is deemed necessary, lump S and I (to represent %susceptible) but never lump %I and %R.
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05 Jul 2024:
Website statistics updated
Statistics for the use of the EUCAST website are updated quarterly.
The total number of page-views has increased over time and is now
between 150 000 and 200 000. We are happy you find the information we
convey via the website useful. More statistics are available.
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04 Jul 2024:
RAST from EUCAST updated to include Salmonella enterica
RAST breakpoints and methods were developed further to include Salmonella enterica in systemic infections.
Some QC criteria were also updated.
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04 Jul 2024:
Two new RDs for published
Rationale Documents for aztreonam-avibactam and cefepime-enmetazobactam available.
Please visit the EUCAST News page to read more.
All changes to the EUCAST website and to AST recommendations and guidance are listed in a table on the EUCAST website!
With kind regards,
EUCAST
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